Designed Experiments for Life Sciences (2 days)

Day 1	Section 1	—	Introduction to Factorial Design
			Brief description of factorial design The factorial design planning process Basics of factorial design (microwave popcorn) Multiple response optimization
Lunch	Section 2	—	Enhancements for Full Factorials
			Replicated full factorial (mouse cell assay) Explanation of power 28 full factorial (assay contaminants) Blocking
	Section 3	—	Fractional Factorials
			Fractional factorials 28-2 fractional factorial (assay contaminants) Setup and aliases Minimum-run resolution V (MR5) designs (stent delivery) Response transformation
Day 2			General Factorials
			Immunofluorescent assay optimization
	Section 4	—	Introduction to Response Surface Design
			Factorial with center points (bench reaction) Introducing Response Surface Methods “RSM” Augmenting to central composite design “CCD” “Good” response surface designs Sizing for precision
	Section 5	—	Response Surface Methodology
			Instructor-led exercise (fluid bed coating) Building the design Details of analysis Optimization Quality by Design “QbD”
Lunch	Section 6	—	Constrained Response Surface
			Constrained design space Optimal design Stent spray coating
	Section 7	—	Quality by Design "QbD"
			Quality by Design Illustrative example (tableting process)
	Section 8	—	Introduction to Mixture Design
			What makes a mixture? Mixture (Scheffé) polynomials Simplex lattice designs (synthetic medium) Constrained mixture (antiseptic)
			Summary
			Next steps

See the DELS course description for further information. To view our public workshops, click here.

Contact Elicia by e-mail or by calling 1.612.746.2038 with any questions.